Sindhu KNC, et al. - Authors sought to provide an update on the impact of rotavirus vaccines in low and middle-income countries (LMICs) on morbidity and mortality in children aged less than 5 years and their cost-effectiveness. Findings revealed marked impact of rotavirus vaccination on hospitalizations and economic burden because of rotavirus gastroenteritis in LMICs. They recommended universal rotavirus vaccination and monitoring the introductions by robust surveillance systems to measure effectiveness and impact.