Katagiri Y, et al. - Researchers examined the links between post-procedural minimal stent area (MSA), assessed by post-procedural intravascular ultrasound (IVUS) and lesion-level outcomes at 2 years in patients with three-vessel disease (TVD) (454 patients with 1,559 lesions) who underwent contemporary PCI in the SYNTAX II study (a multicenter, all-comer, open-label, single arm study). The identified independent predictors of target lesion revascularization (TLR) were smaller post-procedural MSA, creatinine clearance, history of previous stroke, chronic total occlusion, and lesion SYNTAX Score, as revealed in the multivariate analysis. Findings revealed an independent association of a larger post-procedural MSA with the lower rate of TLR at 2 years.