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Impact of physical activity and exercise on bone health in patients with chronic kidney disease: A systematic review of observational and experimental studies

BMC Nephrology Aug 12, 2020

Cardoso DF, Marques EA, Leal DV, et al. - Researchers performed this review to determine the link of both physical activity (PA) and the impacts of different exercise interventions with bone outcomes in chronic kidney disease (CKD). They analyzed observational and experimental researches assessing the link between PA and the impact of regular exercise on bone-imaging or -results in CKD stage 3–5 adults. These studies were identified from EBSCO, Web of Science and Scopus. This analysis involved six observational (including 4 cross-sectional and 2 longitudinal) and seven experimental (2 aerobic-, 5 resistance-exercise trials) studies. Experts identified partial evidence supporting that PA is positively associated with bone outcomes and that bone health is positively impacted by resistance exercise in patients with CKD. Currently, there is a lack of prospective population investigations and long-term randomized controlled trials inquiring about different exercise modalities measuring bone-related parameters as endpoint.

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