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Impact of overweight and obesity on US papillary thyroid cancer incidence trends (1995–2015)

Journal of the National Cancer Institute Dec 13, 2019

Kitahara CM, et al. - From 1995 to 2015, the proportion of papillary thyroid cancer (PTC) incidence attributable to overweight and obesity in the United States was estimated in this study utilizing National Institutes of Health-AARP Diet and Health Study cohort data (n = 457 331 participants, 50–71 years and cancer-free at baseline) as well as the National Health Interview Survey. Researchers noted 1.26-fold and 1.30-fold elevated risks of PTC as well as approximately threefold and greater than fivefold heightened risks of large (> 4 cm) PTCs in relation to overweight (25.0–29.0 kg/m2) and obesity (≥ 30.0 kg/m2), respectively, vs normal weight (18.5–24.9 kg/m2). Findings highlighted the likely important contribution of overweight and obesity to the speedy increase in PTC incidence during 1995–2015. By 2015, overweight and obesity were held accountable for one of every six PTCs diagnosed among adults 60 years or older, including approximately two-thirds of large PTCs.
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