Impact of low skeletal muscle mass and density on short and long-term outcome after resection of stage I-III colorectal cancer
European Journal of Surgical Oncology Jun 14, 2018
van Vugt JLA, et al. - Considering the association of preoperative low skeletal muscle mass and density with increased postoperative morbidity in patients undergoing curative colorectal cancer (CRC) surgery, researchers investigated the long-term effects of low skeletal muscle mass and density. They analyzed in total, 816 patients (53.9% males, median age 70) with stage I-III CRC undergoing surgery, enrolled in a prospective observational cohort study. Findings suggest that in patients undergoing CRC surgery, low skeletal muscle mass and density are associated with short-term but not long-term outcome. Findings thereby suggest emphasizing more on preoperative management of patients at risk for surgical complications, but do not support benefit for long-term outcome.
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