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Impact of low ankle-brachial index on the risk of recurrent vascular events: Insights from the OPTIC Registry

Stroke Mar 16, 2019

Abboud H, et al. - In this investigation, researchers assessed the prevalence of ankle-brachial index (ABI) ≤0.9 (which indicates peripheral artery disease) in nonembolic stroke patients or transient ischemic attack and evaluated the association of low ABI with stroke risk, factors, and recurrent vascular events and death. From over 17 low-income and middle-income countries, patients ≥45 years with acute transient ischemic attack or minor ischemic strokes were recruited consecutively. Of the 3,487 patients enrolled, 22.3% had abnormal ABI (<0.9). Subjects with an ABI of ≤0.9 were more likely to be male, older, and have a history of peripheral artery disease, hypertension, and diabetes mellitus. In this population, patients with low ABI had an increased rate of vascular events and death. Patients at high risk for future events may be identified by screening for ABI in patients with strokes.

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