Chaix I, Manquat E, Liu N, et al. - Given reductions in mean arterial pressure (MAP) are often noted during anesthesia but the influence on possible cerebral hypoperfusion continues to be a matter of debate, and therefore, researchers assessed cerebral perfusion among patients with or without cardiovascular comorbidities (Hi-risk vs Lo-risk) during induction of general anesthesia and during hypotensive episodes. Transcranial Doppler measuring mean blood velocity of the middle cerebral artery (Vm), Bispectral Index with burst suppression ratio (SR) and cerebral Near-Infrared Spectroscopy were included in the monitoring. Experts analyzed prospectively included patients who were scheduled for neuroradiology procedure utilizing standardized target-controlled Propofol-Remifentanil infusion. There were 81 patients in total, including 37 Hi-risk and 44 Lo-risk. The reduction of MAP and Vm was observed in all patients during the induction of anesthesia. A higher reduction in MAP and Vm, and a higher occurrence of SR during induction of anesthesia was reported in Hi-risk patients vs Lo-risk patients. Mainly Hi-rik patients showed increased Vm consequent to the correction of MAP with norepinephrine.