Shamekhi J, et al. - Given that high-risk percutaneous coronary interventions (PCI) in patients with complex coronary artery disease might be facilitated by the use of left-ventricular (LV) hemodynamic support, researchers compared the outcomes of high-risk patients who had protected PCI to those of who had unprotected high-risk PCI. According to the findings, patients who underwent protected PCI demonstrated 1-year outcome that was not different from that observed in patients with less complex procedures without hemodynamic support, although the former group had a more complex coronary anatomy, a higher comorbidity burden, and more often reduced LV function.