Parikh PB, et al. - Researchers determined the influence of female gender on mortality and poor neurologic results in adults with in-hospital cardiac arrest (IHCA). The participants (n = 680) were recruited from an academic tertiary medical center where they underwent ACLS-guided resuscitation during hospitalization for IHCA. In-hospital mortality was assessed as the primary outcome and favorable neurological outcome, defined as a Glasgow Outcome Score of 4 or 5, was the secondary outcome. The study sample comprised of 680 patients, including 418 (61.5%) men and 262 (38.5%) women. Despite the similarity noted in both groups in terms of location of cardiac arrest, initial rhythm, and duration of cardiopulmonary resuscitation, there were lower rates of defibrillation in women. Findings revealed an independent link of the female gender with nearly twofold higher rates of in-hospital mortality and a trend toward lower rates of favorable neurologic outcomes in this prospective, contemporary registry of adults with IHCA.