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Impact of food supplements on early child development in children with moderate acute malnutrition: A randomised 2 x 2 x 3 factorial trial in Burkina Faso

PLoS Medicine Feb 19, 2021

Olsen MF, Iuel-Brockdorff AS, Yaméogo CW, et al. - In this randomised trial involving 1,609 children with moderate acute malnutrition (MAM) in Burkina Faso, researchers sought to examine the effectiveness of supplemental foods, including a comparison of matrix (lipid-based nutrient supplements or corn-soy blend), soy quality (soy isolate or dehulled soy), and content of milk protein (0%, 20%, or 50% of protein). The authors observed that during and after supplementation for the treatment of MAM, child development improved. For language and fine motor development, milk protein was beneficial, although suggested advantages related to soy quality and supplement matrix merit further investigation. Supplement-specific effects were not observed post-intervention, but z-scores continued to improve, implying a sustained overall effect of supplementation.

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