Samuels AM, Odero NA, Odongo W, et al. - Repeated rounds of community-based mass testing and treatment (MTaT) were investigated for their efficacy on malaria infection prevalence in western Kenya. Researchers randomly allocated 20 clusters to three rounds of MTaT per year for two years or control (standard-of-care for testing and treatment at public health facilities along with government sponsored mass long-lasting insecticidal net (LLIN) distributions). During rounds, all households in intervention clusters are visited by community health volunteers and all consenting individuals are tested with a rapid diagnostic test. Treatment was provided with dihydroartemisinin-piperaquine to those with positive results. Both study arms underwent cross-sectional community infection prevalence surveys at baseline and each year after three rounds of MTaT. Outcomes revealed no reduction in malaria parasite prevalence in this high-transmission area in correlation with MTaT performed three times per year over two years.