Impact of CLSI and EUCAST cefepime breakpoint changes on the susceptibility reporting for Enterobacteriaceae
Diagnostic Microbiology and Infectious Disease Aug 31, 2017
Bork JT, et al. - Researchers here determined the effects of different cefepime MIC breakpoints on Enterobacteriaceae cefepime susceptibility and the presence of AmpC and extended–spectrum β–lactamase (ESBL) genes within the cefepime MIC interpretative categories. Obseervations revealed that lower cefepime MIC breakpoints decrease cefepime susceptibility for isolates harboring ESBLs, while sparing the majority of those with AmpCs.
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