Korber MI, Friedrichs KP, Aydin F, et al. - This study was undertaken to explore the incidence of cleft‐like indentations (CLI) and their impact on percutaneous edge‐to‐edge mitral valve (MV) repair (PMVR). Between 11/2012 and 7/2016, researchers conducted a retrospective single-center analysis including a total of 263 patients undergoing PMVR with the MitraClip‐system, MV anatomy was assessed by 3‐dimensional transesophageal echocardiography. The results of this study exhibited that CLI of the MV is common in patients undergoing PMVR, also when presenting mainly with secondary MR. Procedural success rates appear not to be affected, while the number of clips needed to address MR is slightly higher in patients with CLI. For patients with CLI, PMVR appears to be a safe treatment option.