Alt JA, et al. - Experts prospectively assessed objective sleep measures in a cohort of individuals with chronic rhinosinusitis (CRS) in this controlled clinical study. A total of 108 patients with CRS (n=52) and control participants (n=56) were included in the study and enrolled across four institutions. In patients with CRS, total Pittsburgh Sleep Quality Index scores were worse vs control participants. Similarly, upon Epworth Sleepiness Scale score review, patients with CRS were found to have greater daytime somnolence than those in the control group. Except mean oxygen saturation, all differences remained significant after controlling for baseline differences. Findings indicated that there exist differences in both patient-reported and objective sleep measures between patients with CRS and control participants.