Kogawa T, et al. - In the present study, researchers tested the premise that pathological complete response (pCR) rate and worse survival outcomes in primary breast cancer patients would be correlated with an increase in BMI category during neoadjuvant chemotherapy (NAC) via reviewing the medical records of 4,029 subjects with stage I–III breast cancer who had undergone NAC and definitive surgery at the institution between May 1, 1990 and April 30, 2013. Findings revealed that not being able to maintain normal weight during NAC was predictive of poor survival, but not pCR. Maintaining a normal weight during NAC, they suggested, might be important for patients. No relationship was found between BMI change and pCR rate.