Impact of cerebral small vessel disease on functional recovery after intracerebral hemorrhage
Stroke Aug 29, 2019
Venema SMU, Marini S, Lena UK, et al. - Using multivariable logistic and linear regression models, researchers explored the connection of CT–based markers of cerebral small vessel disease with functional outcome and recovery after intracerebral hemorrhage. Using visual rating scales, CT scans of patients in the Ethnic and Racial Variations of Intracerebral Hemorrhage study were assessed for the extent of leukoaraiosis and cerebral atrophy. Data from 2,344 patients—583 with good functional outcome (mRS of 0–2) at discharge and 1,761 with poor functional outcome (mRS of 3–5) at discharge—were included after excluding in-hospital deaths. Findings suggested an association of the extent of cerebral small vessel disease at the time of intracerebral hemorrhage with the poor functional outcome at hospital discharge, and impaired functional recovery from discharge to 90 days poststroke in intracerebral hemorrhage survivors.
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