Li X, Liu Q, Bao W, et al. - Findings indicate that significant fluctuations in blood pressure could lead to alterations in myocardial work (MW) indices to preserve left ventricular systolic function. It is mandatory to evaluate MW indices repeatedly in hypertensive patients with large blood pressure fluctuations.

• This study included 117 participants (34 controls and 83 hypertensive patients) to determine the impact of blood pressure alterations on MW indices in these populations in a day.

• Higher global work index, global constructive work, and global wasted work but lower global myocardial longitudinal strain (GLS) and global work efficiency were detected in participants with hypertension vs controls.

• Those with hypertension exhibited significantly higher absolute changes in blood pressure, GLS, and MW indices, compared with controls.

• A significant univariate correlation was found between blood pressure changes and changes in GLS and MW indices.