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Impact of baseline estimated glomerular filtration rate on inhospital outcomes of patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: A China Acute Myocardial Infarction registry study

Catheterization and Cardiovascular Interventions Jan 17, 2019

Jia S, et al. - Among 10,240 participants from the China Acute Myocardial Infarction registry who had a primary percutaneous coronary intervention from January 2013 to January 2016 for ST segment elevation myocardial infarction, researchers examined the link between in-hospital outcomes and different estimated glomerular filtration rates (eGFRs) and determined an optimal eGFR cutoff value for predicting risk in patients with renal insufficiency. A total of 1,112 (10.9%) patients had eGFR <60 mL/min/1.73 m2. A common occurrence of RI was reported in these patients. A significantly higher incidence of all-cause death and major adverse cardiovascular and cerebrovascular events (MACCEs) was seen in patients with eGFR<60 mL/min/1.73 m2 vs those with eGFR >60 mL/min/1.73 m2. With the decline in eGFR, an increase in the incidence of in-hospital all-cause death and MACCEs was observed in occurrence trend test analysis. eGFR <45 mL/min/1.73 m2 vs eGFR >90 mL/min/1.73 m2 was found to be related to a higher incidence of all-cause death and MACCEs in logistic multivariate-adjusted analysis. For the prediction of in-hospital deaths and MACCEs, an eGFR cutoff value of 45 mL/min/1.73 m2 was suggested.

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