Martí-Sánchez D, Carballeira D, Morales MJ, et al. - Given that bleeding risk stratification represents an unsolved concern in older adults, and anemia may indicate subclinical blood losses that can be exacerbated following PCI, so, researchers prospectively inquired about the contribution of anemia to the risk of bleeding among consecutive patients (n = 448; aged 75 or more years) managed by PCI with no concomitant indication for oral anticoagulation. They determined how WHO-defined anemia influences the incidence of 1-year non-access site-related major bleeding. The prevalence of anemia was estimated to be 39%. The occurrence of a bleeding event was reported in 13.1% of anemic and 5.2% of nonanemic patients. As far as the prediction of bleeding was concerned, no superiority of either PRECISE-DAPT or CRUSADE scores over hemoglobin was evident. Overall, anemia was identified as a powerful predictor of bleeding in this study and was suggested to have potential utility for simplifying tailoring therapies.