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Impact of age on breast cancer mortality and competing causes of death at 10 years follow-up in the adjuvant TEAM trial

European Journal of Cancer Jul 08, 2018

Derks MGM, et al. - The impact of age on breast cancer mortality and other cause mortality 10 years after diagnosis was evaluated in this analysis. Between 2001 and 2006, postmenopausal patients with hormone-receptor positive breast cancer were involved in the Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial. Older age at diagnosis is linked with increasing breast cancer mortality in univariate analysis, but was not significant in multivariable analysis. Researchers found that older patients were at risk of both undertreatment and overtreatment. In the elderly, physicians need to carefully balance harms and benefits of treatment.

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