Hui S, et al. - Researchers assessed the prognostic significance of IMP3 and Fli-1 in malignant peritoneal mesothelioma (MPeM). For this investigation, diagnostic biopsies of 44 MPeM subjects were centrally gathered and were immunohistochemically examined for expression of IMP3, Fli-1, and Ki-67. They found that tumor-directed treatment, a lower PCI, Stage I, lower Ki-67LI and lower level IMP3 expression had a statistically significant positive effect on overall survival. The main finding of this study was that IMP3, along with tumor-directed treatment protocols, was a powerful prognosticator in patients with MPeM.