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Immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa facilitates diagnosis of pediatric ulcerative colitis

Digestive Diseases and Sciences Mar 30, 2018

Fabian O, et al. - Authors sought to examine the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn’s disease (CD) and ulcerative colitis (UC) and its utility as a predictor of future differentiation in patients with inflammatory bowel diseases (IBD) unclassified (IBDU). Findings displayed that the histopathological assessment of biopsy with rectal CD30+ count served as a reliable and simple method that possibly assisted in the differential diagnosis among IBD subtypes in children with IBD.
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