Nelson DR, et al. - In this prospective, single-center, cohort study, researchers assessed antibody response to a quadrivalent meningococcal conjugate vaccine (MenACWY-D) in adolescents (11–22 years old) with a functioning kidney transplant for at least 3 months and no previous meningococcal vaccination. The definition of seropositivity was a titer ≥ 1:8 at baseline, and seroconversion was a fourfold or greater increase in antibody titer from baseline at 4 weeks post-vaccination. Findings indicated that response to MenACWY-D in adolescents with a kidney transplant may be inadequate. Moreover, these subjects may experience more rapid declines in antibody titers, relative to healthy adolescents.