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Immunogenicity of glycosylphosphatidylinositol-anchored micronemal antigen in natural Plasmodium vivax exposure

Malaria Journal Sep 01, 2017

Changrob S, et al. – Researchers here demonstrated the antibody responses and cellular immunity against P. vivax glycosylphosphatidylinositol (GPI)–anchored micronemal antigen (PvGAMA) during and post–infection to support the hypothesis that this antigen can induce an immune response in natural exposure. They realized that PvGAMA had potential to induce an immune response both humoral and cellular immunity in naturally acquired P. vivax infection individuals during infection and post–infection. Therefore, they suggested PvGAMA as a vaccine candidate to stimulate immune response against P. vivax infection.
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