Deonizio JMD, et al. - Researchers assessed a possible role of immune privilege (IP) in folliculotropic mycosis fungoides (FMF) analyzing the major histocompatibility complex (MHC) expression. The hypothesis of disruption of immune privilege based on the lower expression of HLA-G and higher expression of MHC-II in the follicular epithelium in mycosis fungoides vs alopecia areata and normal scalp skin was supported in the findings. Experts noted that the lack of difference between FMF and conventional mycosis fungoides (CMF) groups did not support the role of these molecules as a driver of folliculotropism. A difference in the expression of MHC molecules between neoplastic and inflammatory infiltrates was seen.