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Imbalance in DNA repair machinery is associated with BRAFV600E mutation and tumor aggressiveness in papillary thyroid carcinoma

Molecular and Cellular Endocrinology Dec 17, 2017

Lutz BS, et al. - This study was performed to examine whether an imbalance in DNA repair machinery was correlated with BRAFV600E mutation and tumor aggressiveness in papillary thyroid carcinoma (PTC). The authors found an association between DNA repair gene expression in PTC and aggressive clinicopathological features and BRAFV600E mutation.
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