Mavrogeni S, et al. - This study was designed to shed light on the imaging patterns of cardiovascular lesions in patients with mixed connective tissue disease (MCTD) and cardiovascular symptoms with or/ without abnormal routine non-invasive evaluation. The presence of myocardial lesions in MCTD patients with cardiac symptoms including myocardial infarction, inflammation, diffuse subendocardial fibrosis and diffuse perfusion defects, could be revealed by cardiovascular magnetic resonance study (CMR), necessitating further cardiac investigation and/or treatment. The CMR lesions were subendocardial or transmural LGE following the distribution of coronary arteries, intramyocardial LGE and diffuse subendocardial LGE in systemic lupus erythematosus-rheumatoid arthritis, myositis and scleroderma like MCTD, respectively.