Wang PL, et al. - In this retrospective review, researchers, for the first time, explored the influence of extracellular mucus contents in pure mucinous breast carcinoma (PMBC) on its imaging features by multi-imaging technologies. The study sample consisted of available images from 25 patients with 25 PMBC tumors, with ultrasonography (US), ultrasonic elastography (USE), mammography, and breast-specific gamma imaging (BSGI) available for 25, 15, 11, and 8 patients respectively. Findings revealed that imaging features correlated with extracellular mucus content in PMBC tumors in US, USE, and BSGI, among which the most relevant feature is the L/N value using BSGI imaging. There was no significant correlation between mucus content and mammography imaging feature. Overall, the investigators suggested that multi-imaging combination features can provide more information about mucus contents within PMBC.