Luporini RL, de A. Rodolpho JM, Kubota LT, et al. - Researchers herein examined adult patients who were hospitalized with COVID-19 and stratified according to age (older or younger than 65 years) in order to determine circulating levels of inflammatory cytokines and correlations between these markers of inflammation and comorbidities. In this retrospective cohort study, they assessed 142 COVID-19 patients consecutively admitted to the University Hospital of the Federal University of São Carlos, from July to October 2020. Per findings, serum levels of IL-6 and IL-10 were higher in older adults with COVID-19. An independent correlation of IL-10 was observed with age and severity of the disease. No direct correlation of IL-6 with age was observed. Association of comorbidity index with IL-6 levels was observed among those aged 65 and over.