Lamberts A, Kotnik N, Diercks GFH, et al. - Researchers conducted the study for analyzing IgE in serum and skin of nonbullous pemphigoid (NBP) and bullous pemphigoid (BP) patients. In the serum of 68 NBP and 50 BP patients, enzyme linked immunosorbent assay (ELISA) examined total IgE and pemphigoid‐specific IgE. Sera of 25 patients with pemphigus and 25 elderly patients with pruritus have been included as controls. According to findings, total IgE was increased in 63% of NBP and 60% of BP patients, and in 20% of pemphigus controls, as well as 60% of elderly controls. This supports IgE‐dependent mechanisms common to both diseases, such as pruritus, as IgE was present in the serum and skin of both NBP and BP patients. Whether IgE contributes to blister formation in BP, however, remains to be elucidated.