Aizenberg E, et al. - Authors identified a subset of RA-specific features in a case-control setting and validated them in a longitudinal cohort of arthralgia patients. They studied the difference in frequency of MRI-detected inflammation (bone marrow oedema, synovitis, tenosynovitis) between RA patients and controls in 61 features across the wrist, metacarpophalangeal, and metatarsophalangeal joints. A considerable reduction of scoring efforts was provided with subset of 30 MRI-detected inflammatory features, dominated by (teno) synovitis, without compromising accuracy for prediction of arthritis development in clinically suspect arthralgia (CSA) patients.