Gal R, van Velzen SGM, Hooning MJ, et al. - Researchers conducted this multicenter cohort study to assess the correlation of coronary artery calcium (CAC) with cardiovascular disease (CVD) and coronary artery disease (CAD) in patients with breast cancer. Of the 15,915 candidates involved in this study, the mean (SD) age at CT scan was 59.0 (11.2; range, 22-95) years, and 15,879 (99.8%) were women. The link between CAC and CVD was strongest in patients treated with anthracyclines and patients who received a radiation boost. According to this cohort study, the presence of CAC on breast cancer radiotherapy planning CT scan results was linked to CVD, particularly CAD. Automated CAC scoring in radiotherapy planning CT scans may be used as a quick and low-cost tool to identify patients with breast cancer who are at increased risk of CVD, allowing for the implementation of CVD risk-mitigation strategies with the goal of reducing the risk of CVD burden after breast cancer.