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Identification of pathological complete response after neoadjuvant chemotherapy for breast cancer: Comparison of greyscale ultrasound, shear wave elastography, and MRI

Clinical Radiology Jul 09, 2018

Evans A, et al. - In this prospective cohort study, researchers evaluated the value of post-treatment shear-wave elastography (SWE) parameters (maximum stiffness [Emax], mean stiffness [Emean], and standard deviation [SD]) vs greyscale ultrasonography (US) and magnetic resonance imaging (MRI) in detecting pathological complete response (pCR) to neoadjuvant chemotherapy (NACT) in breast cancer. For this investigation, 80 subjects receiving NACT for breast cancer had baseline and post-treatment US, SWE, and MRI exams. Data reported that SWE combined with greyscale US has promise for end-of-treatment identification of response to NACT in women with breast cancer, with similar accuracy to breast MRI. After NACT, this technique could be used to inform surgical decision-making.

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