Stanley S, et al. - Using electrochemiluminescence (ECL), researchers estimated 48 urine samples to study low-abundance urinary protein biomarkers in lupus nephritis (LN). They elected interleukin-7 (IL-7), IL-12p40, IL-15, interferon-γ–inducible protein 10 (IP-10), and thymus and activation-regulated chemokine (TARC) validation of study. They noted a significant elevation of urinary IL-7, IL-12p40, IL-15, IP-10, and TARC levels active LN cases as compared to candidates with inactive SLE and healthy controls. These biomarkers were found in correlation with the renal Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) and physician's global assessment of disease activity. They also reported a more frequent rise of all 5 urinary proteins in LN vs controls with other chronic kidney diseases.