Identification of ST3AGL4, MFHAS1 CSNK2A2 and CD226 as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning
Annals of Rheumatic Diseases Apr 13, 2018
Wang YF, et al. - Experts sought to validate the newly identified 10 novel loci associated with systemic lupus erythematosus (SLE) and evaluate the role of SLE genetics in drug repositioning through genome-wide association studies (GWAS). As per data, 3 novel loci, ST3AGL4, MFHAS1 and CSNK2A2, associated with SLE were identified and demonstrated the role of SLE GWAS findings in drug repositioning. The SLE risk genes were seen more likely to be interacting proteins with targets of approved SLE drugs. The association of the CD226 locus with SLE was also confirmed.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries