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ICU discharge screening for prediction of new-onset physical disability - a multinational cohort study

Acta Anaesthesiologica Scandinavica Mar 01, 2020

Milton A, Schandl A, Soliman I, et al. - With an intent to construct a method for predicting new-onset physical disability at ICU discharge, researchers undertook this multinational prospective cohort analysis in 10 general ICUs in Sweden, Denmark and the Netherlands. Inclusion criteria included adult patients with an ICU stay ≥ 12 hours. Overall patients were 572 in total. The incidence of new-onset physical disability was estimated to be 19%. One sole predictor for the outcome was provided by univariable and multivariable modeling: physical status at ICU discharge, evaluated with the five first items of the Chelsea Critical Care Physical Assessment Tool (CPAx), a higher score suggesting a lower risk, with an area under the receiver operating characteristics curve of 0.68. Negative predictive value for a low-risk group (CPAx score > 18) and positive predictive value for a high-risk group (CPAx score ≤ 18) were identified to be 0.88 and 0.32, respectively. Findings revealed a moderate AUC of the ICU discharge evaluation defined in this study but this ICU discharge assessment may be beneficial to rule out patients unlikely to require physical interventions after ICU.
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