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Hypoxic liver injury after in- and out-of-hospital cardiac arrest: Risk factors and neurological outcome

Resuscitation Mar 07, 2019

Roedl K, et al. - Incidence, outcome and functional outcome of patients with hypoxic liver injury (HLI) after in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA) were assessed via analyzing a cardiac arrest registry data over a 7-year period. They identified 1068 patients after IHCA and OHCA with the return of spontaneous circulation (ROSC); HLI was reported in 219 (21%) patients among these. This suggests a frequent occurrence of new onset of HLI after IHCA and OHCA. As per multivariate regression analysis, independent predictors for occurrence of HLI were time-to-ROSC, presence of cardiac failure and Charlson comorbidity index. Increased mortality, unfavourable neurological and overall outcome were noted in correlation with HLI.
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