Zhang W, Chen M, Li H, et al. - Researchers undertook this prospective randomized controlled trial to determine whether hypoxic preconditioning (HPC) would decrease lung injury in patients undergoing thoracoscopic lobectomy. Random assignment of 70 patients undergoing elective thoracoscopic lobectomy to the HPC group or the control group was done. The HPC intervention included the application of three cycles of 5-min hypoxia and 3-min ventilation to the nondependent lung. The PaO₂/FiO₂ (fraction of inspired oxygen) ratio was assessed as the primary outcome and postoperative pulmonary complications, pulmonary function, and duration of hospital stay were evaluated as secondary outcomes. Findings revealed that the consequences of the employment of HPC were improved postoperative oxygenation, improved recovery of pulmonary function, and decrease in the duration of hospital stay in this patient population.