Campbell H, et al. - Using data from the Health Utilities Index (HUI), which were collected during the 6-year to 7-year follow-up of surviving children in the Total Body Hypothermia for Neonatal Encephalopathy (TOBY) Trial, the researchers evaluated the impact of hypothermic neural rescue at birth on health-related quality of life (HRQL) in middle childhood. Participants in the study were 145 children whose parents consented and returned the questionnaire. Data reported that non-significant differences in HRQL favouring moderate hypothermia supported the clinical findings of the TOBY Children Study. In addition, it also provided previously unavailable data of interest to parents, health policy makers and health economists who may now wish to re-evaluate the long-term cost-effectiveness of hypothermia for perinatal asphyxia.