Hyperuricemia is associated with acute kidney injury and all-cause mortality in hospitalized patients
Nephrology Jan 19, 2019
Kang MW, et al. - Researchers retrospectively reviewed data from 18,444 hospitalized patients to assess the relationship between uric acid and the risk of acute kidney injury (AKI) and mortality in hospitalized patients. They found that hyperuricemia increased the risks of AKI and all-cause mortality in hospitalized patients. Calculating the odds ratio (OR) for AKI and the hazard ratio (HR) for all-cause mortality based on the uric acid quartiles, they identified that the fourth quartile group (male, UA > 6.7 mg/dL; female, UA > 5.4 mg/dL) had a higher risk of AKI, had more patients who did not recover from AKI, and had a higher risk of all-cause mortality vs the first quartile group (male, UA < 4.5 mg/dL; female, UA < 3.6 mg/dL).
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