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Hyperuricemia and its association with adiposity and dyslipidemia in Northwest China: Results from Cardiovascular Risk Survey in Xinjiang (CRS 2008–2012)

Lipids in Health and Disease Apr 07, 2020

Liu F, Du GL, Song N, et al. - Researchers performed this inquiry among non-hospitalized people (aged ≥ 35 years) in Xinjiang, a northwest part of China based on the Cardiovascular Risk Survey (CRS 2008–2012), to investigate the prevalence of hyperuricemia as well as its link with adiposity and dyslipidemia. Overall 16,611 participants were recruited and 14,618 were included (mean age of 50.5 ± 12.6 years, 46.6% was males). The overall prevalence of hyperuricemia was estimated to be 9.1%; 11.8% in men and 6.7% in women. In Han, Uygur, and Kazakh Chinese, hyperuricemia prevalence was found to be 15.4%, 4.6%, and 5.5%, respectively, which corresponding to a respective mean serum uric acid (sUA) levels of 306.2 ± 86.9, 249.4 ± 76.1 and 259.8 ± 78.7 μmol/L. Higher levels of sUA were seen among participants with diabetes, hypertension or hypertriglyceridemia and higher blood urea nitrogen, estimated glomerular filtration rate, fasting blood glucose, triglycerides, total cholesterol. In the economically developing regions of northwest China, it was evident that hyperuricemia is prevalent. Hyperuricemia was found to be related to advanced age, male ender and general metabolic and cardiovascular risk factors. A rise in hyperuricemia risk was observed in relation to the presence of obesity and dyslipidemia.

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