Hypertriglyceridemia is associated with an increased risk of peripheral arterial revascularization in high-risk statin-treated patients: A large administrative retrospective analysis
Clinical Cardiology Aug 07, 2019
Toth PP, et al. - In this large retrospective administrative claims analysis, researchers analyzed the Optum Research Database to further explore the link between hypertriglyceridemia and peripheral arterial revascularization in high-risk statin-treated patients. The participants aged ≥ 45 years and had diabetes and/or atherosclerotic cardiovascular disease. Using propensity score matching, they matched patients with triglyceride level (TG) ≥ 150 mg/dL to a comparator cohort with TG < 150 mg/dL and high-density lipoprotein cholesterol > 40 mg/dL (n = 23,181 in each cohort). In this study, peripheral arterial revascularization was significantly predicted by elevated TG ( ≥ 150 mg/dL) and high TG (200-499 mg/dL) among high-risk statin-treated patients.
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