Oliver JR, Lieberman SM, Tam MM, et al. - Researchers utilized the National Cancer Data Base to assess patterns of human papillomavirus (HPV) testing as well as its link with survival in patients suffering from sinonasal squamous cell carcinoma (SNSCC). They identified all SNSCC patients (n = 6,458) who received a diagnosis between 2010 and 2016. This study included only 1,523 cases (23.6%) that were tested for HPV. The study sample had a median age of 64 years and comprised the majority of cases with advanced-stage tumors. Of the final study cohort, 31.5% (447 of 1418 cases) were HPV-positive SNSCC. Findings revealed that HPV testing was performed currently only in a minority of patients with SNSCC. However, a sizable percentage of cases with SNSCC may be HPV associated. Improved overall survival was observed in relation to HPV-positive SNSCC. In patients suffering from SNSCC, routine HPV testing may be warranted.