Zhang M, Dai W, Li Z, et al. - Researchers sought to determine the expression as well as cellular functions of heat shock 70 kDa protein 4 (HSPA4) in colorectal cancer (CRC). They found significantly elevated HSPA4 expression at the RNA and protein levels in CRC tissues vs noncancerous tissues. HSPA4 expression was identified to be positively related to tumor stage and its high expression of HSPA4 suggested poor patient prognosis. Findings showed that HSPA4 has clinical significance in CRC. Experts found that HSPA4 impacted proliferation, migration and survival, and thereby contributed to CRC tumorigenesis. Therefore, HSPA4 was concluded to be a novel prognostic indicator and also a promising treatment target in CRC.