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HSP72 functionally inhibits the anti-neoplastic effects of HDAC inhibitors

Journal of Dermatological Science Feb 02, 2018

Fujii K, et al. - This trial was conducted to ascertain the mechanisms responsible for the role of heat shock 70 kDa protein 1A (HSPA1A, also known as HSP72) in the resistance of histone deacetylase inhibitors (HDACi). The authors found that the HDACi-induced apoptosis was inhibited by HSP72.
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