Wright TC, et al - A total of 14,153 women of age 21–34 years were examined to study the consequence of human papillomavirus (HPV) vaccination in a cervical cancer screening population from the USA-based, Onclarity Trial. They reported a lower prevalence of overall HPV, HPV16, 18, 31, and 33/58 in vaccinated females for each age group whereas a significant difference was noted in vaccinated women for all ages combined. In vaccinated women, the cytologic low-grade squamous intraepithelial lesion (LSIL) or worse was lower, as was cervical intraepithelial neoplasia prevalence correlated with HPV 16 or 18.