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How does gestational age affect growth and body composition of preterm twins?

Pediatric Research Aug 15, 2019

Liotto N, Roggero P, Giuliani F, et al. - In this investigation, researchers compared growth and body composition (BC) of twin and singleton preterm infants from birth to 3 months according to gestational age (GA), as well as assessed the impact of chorionicity and mode of feeding on twins’ BC. They performed anthropometric measurements and BC at term and 3 months in preterm infants (GA < 37 weeks). They categorized infants as: extremely, very, moderate and late preterm infants. Feeding mode was recorded as any human milk feeding compared with formula feeding. The study sample consisted of 576 preterm infants (223 twins). Multichorionic infants had a fat-free mass (FFM) deficit vs monochorionic and dichorionic at term, while at 3 months no differences were found. FFM at term was negatively linked to being twin and formula-fed. Born before the GA of 34 weeks, twins and singletons showed comparable anthropometry and BC. Conversely, in comparison with singletons, twin late-preterm infants showed distinct growth and BC.
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