Salomao RC, et al. - During this trial, researchers resolved to investigate the existence of an association between homocysteine, folate, high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor alpha and inflammatory proteins with nutritional status and cardiovascular risk in childhood-onset systemic lupus erythematosus (c-SLE). Results demonstrated that the cardiovascular disease (CVD) risk parameters were worse in c-SLE. As per the outcomes, a less protective CVD proteomic profile was discovered in lupus clusters with the worst metabolic profile (LCWMP).