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Home vs hospital narrowband UVB treatment by a hand-held unit for new-onset vitiligo: A pilot randomized controlled study

Photodermatology, Photoimmunology and Photomedicine Feb 08, 2020

Liu B, et al. - In this pilot randomized controlled study involving 100 individuals, researchers contrasted the safety and effectiveness of narrowband ultraviolet B (NB-UVB) phototherapy in home vs in hospital for the management of limited new-onset vitiligo. Individuals with new-onset vitiligo (< 3 months) with < 5% body surface area involvement were selected and randomly assigned to either a home-based or a hospital-based treatment group. According to results, adverse events like painful erythema, burning, blistering, and excessive hyperpigmentation were more often noted in the home-based treatment group vs in the hospital-based treatment group. Following 7 weeks of treatment, the cost of phototherapy in hospital surpassed the cost of home phototherapy. Home NB-UVB phototherapy treatment was as effective as hospital treatment, but it did show cost-effectiveness and better compliance. Nonetheless, patient awareness should be improved to prevent over-exposure to UVB and associated adverse events.
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