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Histopathological and immunohistochemical study of malignant lymphomas

Hematological Oncology Jun 20, 2019

Galainena JJJ, et al. - Using the immunohistochemical technique, researchers intended to classify the various anatomopathological entities of malignant lymphomas. They analyzed 1813 biopsies and found that the most frequent immunophenotypic type was Non-Hodgkin's B Cell Lymphomas (1303 cases)(71,86%). A total of 1184 cases (65,03%) were B Cell Lymphomas CD20 positive. Diffuse Large B Cell Lymphomas (649 cases)(35,79%) was the most frequent histopathological type. In the group of Non-Hodgkin´s T Cell Lymphomas (137 cases in total)(7,55%), the most principal types were Peripheral T Cell Lymphomas (76 cases) and Anaplastic Large Cell Lymphomas (61 cases). Findings revealed that the extranodal location were 868 cases (47,87%) and the most common site diagnosed in this group was the Head and Neck location (180 cases) (20,73%). Over 12 years of daily work in the Immunohistochemistry Laboratory at the Pathology Department, the different histologic types, location and frequencies of the lymphomas studied are shown in this study.
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